Magnetic Actuators and Suspension for Space Vibration Control

The research on microgravity vibration isolation performed at the University of Virginia is summarized. This research on microgravity vibration isolation was focused in three areas: (1) the development of new actuators for use in microgravity isolation; (2) the design of controllers for multiple-degree-of-freedom active isolation; and (3) the construction of a single-degree-of-freedom test rig with umbilicals. Described are the design and testing of a large stroke linear actuator; the conceptual design and analysis of a redundant coarse-fine six-degree-of-freedom actuator; an investigation of the control issues of active microgravity isolation; a methodology for the design of multiple-degree-of-freedom isolation control systems using modern control theory; and the design and testing of a single-degree-of-freedom test rig with umbilicals

Design of a Long-Stroke Noncontact Electromagnetic Actuator for Active Vibration Isolation

A long-stroke moving coil Lorentz Actuator was designed for use in a microgravity vibration isolation experiment. The final design had a stroke of 5.08 cm (2 in) and enough force capability to isolate a mass of the order of 22.7-45.4 kg. A simple dynamic magnetic circuit analysis, using an electrical analog, was developed for the initial design of the actuator. A neodymium-iron-boron material with energy density of 278 T-kA/m (35 MGOe) was selected to supply the magnetic field. The effect of changes in the design parameters of core diameter, shell outer diameter, pole face length, and coil wire layers were investigated. An extensive three-dimensional finite element analysis was carried out to accurately determine linearity with regard to axial position of the coil and coil current levels. The actuator was constructed and tested on a universal testing machine. Example plots are shown, indicating good linearity over the stroke of approximately 5.08 cm (2 in) and a range of coil currents from -1.5 A to +1.5 A. The actuator was then used for the microgravity vibration isolation experiments, described elsewhere

Design Of Journal Bearings For Rotating Machinery

PaperPg. 25-45.Rotating machinery is often subject to vibrations due to critical speeds, unbalance, and instability. Usually the least expensive modification of a machine to make is the bearing. A wide variety of bearings have been developed to combat some of the different types of vibration problems. This paper discusses the geometry and theoretical and experimental results which have been obtained for a number of bearing types. The three main bearing types discussed in this work are multilobe, pressure dam, and tilting pad bearings. A bearing summary chart indicating some of the advantages and disadvantages of these bearing types as well as others is included in the paper

Homogenization of a model for the propagation of sound in the lungs

International audienceIn this paper, we are interested in the mathematical modeling of the propagation of sound waves in the lung parenchyma, which is a foam-like elastic material containing millions of air-filled alveoli. In this study, the parenchyma is governed by the linearized elasticity equations, and the air by the acoustic wave equations. The geometric arrangement of the alveoli is assumed to be periodic with a small period ε > 0. We consider the time-harmonic regime forced by vibrations induced by volumic forces. We use the two-scale convergence theory to study the asymptotic behavior as ε goes to zero and prove the convergence of the solutions of the coupled fluid-structure problem to the solution of a linear-elasticity boundary value problem

Subsynchronous Vibration Problem And Solution In Multistage Centrifugal Compressor.

LecturePg. 65-74The investigation of a subsynchronous vibration problem encountered in a six stage centrifugal compressor is discussed. At a running speed of approximately 9000 rpm, a subsynchronous vibration (at 4200 rpm) of nearly two times the synchronous vibration level was encountered. A systematic program was undertaken to identify the problem and correct it. A detailed analysis of the floating ring annular oil seals, balance piston labyrinth seals and impeller aerodynamic cross coupling was conducted. The oil seals were identified as the primary cause of the subsynchronous vibration due to lock up, and a modified seal design incorporating circumferential grooves was developed. This radically reduced the seal cross coupled stiffness. Further, a modified bearing design was investigated to increase the rotor logarithmic decrement. Changes were implemented in the compressor with the result of no subsynchronous vibrations for the operating conditions of the compressor thus far

Design and Characterization of a Centrifugal Compressor Surge Test Rig

A detailed description of a new centrifugal compressor surge test rig is presented. The objective of the design and development of the rig is to study the surge phenomenon in centrifugal compression systems and to investigate a novel method of surge control by active magnetic bearing servo actuation of the impeller axial tip clearance. In this paper, we focus on the design, initial setup, and testing of the rig. The latter two include the commissioning of the rig and the experimental characterization of the compressor performance. The behavior of the compressor during surge is analyzed by driving the experimental setup into surge. Two fundamental frequencies, 21 Hz and 7 Hz, connected to the surge oscillation in the test rig are identified, and the observed instability is categorized according to the intensity of pressure fluctuations. Based on the test results, the excited pressure waves are clearly the result of surge and not stall. Also, they exhibit the characteristics of mild and classic surge instead of deep surge. Finally, the change in the compressor performance due to variation in the impeller tip clearance is experimentally examined, and the results support the potential of the tip clearance modulation for the control of compressor surge. This is the first such demonstration of the feasibility of surge control of a compressor using active magnetic bearings

Disruption of TLR3 Signaling Due to Cleavage of TRIF by the Hepatitis A Virus Protease-Polymerase Processing Intermediate, 3CD

Toll-like receptor 3 (TLR3) and cytosolic RIG-I-like helicases (RIG-I and MDA5) sense viral RNAs and activate innate immune signaling pathways that induce expression of interferon (IFN) through specific adaptor proteins, TIR domain-containing adaptor inducing interferon-β (TRIF), and mitochondrial antiviral signaling protein (MAVS), respectively. Previously, we demonstrated that hepatitis A virus (HAV), a unique hepatotropic human picornavirus, disrupts RIG-I/MDA5 signaling by targeting MAVS for cleavage by 3ABC, a precursor of the sole HAV protease, 3Cpro, that is derived by auto-processing of the P3 (3ABCD) segment of the viral polyprotein. Here, we show that HAV also disrupts TLR3 signaling, inhibiting poly(I:C)-stimulated dimerization of IFN regulatory factor 3 (IRF-3), IRF-3 translocation to the nucleus, and IFN-β promoter activation, by targeting TRIF for degradation by a distinct 3ABCD processing intermediate, the 3CD protease-polymerase precursor. TRIF is proteolytically cleaved by 3CD, but not by the mature 3Cpro protease or the 3ABC precursor that degrades MAVS. 3CD-mediated degradation of TRIF depends on both the cysteine protease activity of 3Cpro and downstream 3Dpol sequence, but not 3Dpol polymerase activity. Cleavage occurs at two non-canonical 3Cpro recognition sequences in TRIF, and involves a hierarchical process in which primary cleavage at Gln-554 is a prerequisite for scission at Gln-190. The results of mutational studies indicate that 3Dpol sequence modulates the substrate specificity of the upstream 3Cpro protease when fused to it in cis in 3CD, allowing 3CD to target cleavage sites not normally recognized by 3Cpro. HAV thus disrupts both RIG-I/MDA5 and TLR3 signaling pathways through cleavage of essential adaptor proteins by two distinct protease precursors derived from the common 3ABCD polyprotein processing intermediate

Structure of a Murine Norovirus NS6 Protease-Product Complex Revealed by Adventitious Crystallisation

Murine noroviruses have emerged as a valuable tool for investigating the molecular basis of infection and pathogenesis of the closely related human noroviruses, which are the major cause of non-bacterial gastroenteritis. The replication of noroviruses relies on the proteolytic processing of a large polyprotein precursor into six non-structural proteins (NS1–2, NS3, NS4, NS5, NS6pro, NS7pol) by the virally-encoded NS6 protease. We report here the crystal structure of MNV NS6pro, which has been determined to a resolution of 1.6 Å. Adventitiously, the crystal contacts are mediated in part by the binding of the C-terminus of NS6pro within the peptide-binding cleft of a neighbouring molecule. This insertion occurs for both molecules in the asymmetric unit of the crystal in a manner that is consistent with physiologically-relevant binding, thereby providing two independent views of a protease-peptide complex. Since the NS6pro C-terminus is formed in vivo by NS6pro processing, these crystal contacts replicate the protease-product complex that is formed immediately following cleavage of the peptide bond at the NS6-NS7 junction. The observed mode of binding of the C-terminal product peptide yields new insights into the structural basis of NS6pro specificity

Tilting-Pad Journal Bearings—Frequency-Dependent Dynamic Coefficients and Pivot Flexibility Effects

Tribologists have generally accepted that the dynamic modeling of tilting-pad journal bearings (TPJB) must consider the frequency dependency of the dynamic properties. Industrial compressors, turbines, and other rotating machines are subjected to instability drivers, such as blades, impellers, and seals, leading to dominant vibratory frequencies that are generally quite different from rotational frequency. Though the literature has provided related methods and numerical results, full understanding of the physics of TPJB frequency dependency is not generally available to the design community, and theorists and experimentalists are often not in agreement. This investigation hinges on a single-pad, two degree-of-freedom model that creates a basis for understanding the various geometries and operating conditions related to frequency dependency for a full bearing. The analytical results indicate that both stiffness and damping coefficients show frequency dependency, and that the dependency is primarily associated with the pad rotational damping and the flexibility of the pivot contact region that provides support for the pad. Understanding the role of pivot flexibility in combination with the fluid film provides a key to improving agreement between theory and experiment. This article is a revised and expanded version of the paper presented at the ASME 2019 Turbo Expo in Phoenix, Arizona from 17 to 21 June. The paper number was GT2019-90195 and it was titled “On the Frequency Dependency of Tilting-Pad Journal Bearings”